Vol. 6, Issue 7 (2017)

Author(s):
Azhagu Raj R, M Gomathi, A Prakasam, Krishna Priya, V Narayanayyar, P Mahesh and S Siva Subramanian

Abstract:
Phytochemical screening and biological activity prediction provide imperative ideas for the development of new drug against deadly diseases. The medicinal plant Hyptis suaveolens extract was prepared by cold percolation method by using polar and non-polar solvents .The biological activity and pharmacologically active major compounds present in the medicinal plant H. suaveolens were studied by using chem-informatics tools. In this study, the phytochemical analysis results showed that thirteen (13) secondary metabolites of present in the methanolic extract, followed by aqueous extract (12) and acetone extract (11). The PASS predicted pharmacological activities of the compounds beta-caryophyllene, sabinene, beta-pinene, and eucalyptol showed that they are Analeptic, Analgesic Antieczematic, Antipruritic, Antipruritic, Allergic, Antiprotozoal (Leishmania), and antifungal, antiparasitic and anti-inflammatory activities. This suggests that the medicinal plant H. suaveolens could be used to develop the novel drugs in near future for the betterment of mankind.