Vol. 6, Issue 10 (2017)

Author(s):
OI Yurchyshyn, GV Rusko and RV Kutsyk

Abstract:
Antimicrobial activityof sea lavender species growing in the Black Sea area, Limonium meyeri (Boiss.) O. Kuntze. and Limonium hypanicum Klok., wasrevealed by agar microdiffusion screening assay. The sea lavender root extracts are much more active against various bacteria and Candida yeasts comparing with aerial parts extracts. Acetone root extracts and aethyl acetate fractions of 70% aqueous-acetone acetone ‘extracts showed antimicrobial activity against methicillin resistant and sensitive clinical isolates of S. aureus and coagulase-negative staphylococci with MIC₉₀ 250 mg/ml. For gram-negative bacteria MICs of these extracts ranged from 250 to 1,000 mg/ml. Bactericidal, activity of Limonium hypanicum root extract against P. acnes was noticed at dilutions 1:640-1:1,280. It was the same against the both antibiotic sensitive ATCC 6919 and multiple resistant clinical strains of P. acnes. Tannins or free gallic and ellagic acids may be responsible for the antibacterial activity of tested Limonium species roots.