Vol. 11, Issue 10 (2022)

Comparative evaluation of chromic catgut, Polyglycolic acid (PGA), Polyglactin 910 (PG 910) and Polydioxanone (PDS) absorbable sutures for laparotomy wound closure in canines were studied. Laparotomy was conducted for Ovariohysterectomy. There was non-significant difference in Physiological (Respiratory rate, Heart rate and Rectal temperature) and Haematological parameter (TEC, Hb, PCV, TLC). Group III animal had lesser neutrophil count when compared to group I and group IV animals, at 48 hours interval highest neutrophilia was observed in group IV animal followed by group I, group III and group II animal respectively. However, the neutrophil counts on 14^th day fluctuated within normal physiological limit. The group III animal had relative lymphocytopenia when compared to group I and group II animal. On 14^th day relative lymphocytopenia revealed only in group IV animal. There was significant (P≤0.01) increase in aspertate aminotransferase level in all the groups of animal on 14^th day when compared to 0 hours. The increased level was within the physiological limit in group II and IV animals. Group I and group III animal had higher aspertate aminotransferase level than the normal physiological limit. There was significant (P≤0.05) increase in lactate dehydrogenase level in all the groups of animal when compared to pre-operative level. However, the level of lactate dehydrogenase remained within the normal physiological limit in all the groups of animal. The comparison of creatine phosphokinase (CPK) between the group showed that, group II animals had significantly (P≤0.05) lower CPK level when compared to group I animal. The group I animal had significantly (P≤0.05) lower creatine phosphokinase when compared to group III and group IV animals.