Vol. 7, Issue 1 (2018)

Author(s):
Stasyshyn AR

Abstract:
Introduction. The relationship between the hiatal hernia and the gastroesophageal reflux disease (GERD) is established. It is advisable to develop an accessible non-invasive diagnostic method for this combined pathology. Materials and methods. The results of the diagnosis of hiatal hernia, associated with GERD, were analyzed with the help of the determination of ionized calcium in saliva. Results and discussion. It has been established that in the saliva of patients with hiatal hernia, the calcium content was increased by 100.9% compared to the control group. Such a significant increase in the level of calcium in the saliva of patients with hiatal hernia may be due to the fact that the development of this pathology is a disorder of calcium homeostasis. Conclusions. It has been found that the calcium content in the saliva of patients with hiatal hernia exceeded the norm almost twice. Thus, the determination of calcium content in saliva can be used as a simple non-invasive diagnostic marker of hiatal hernia associated with GERD.