Abstract:The present experiment was undertaken to evaluate the effect of fertigation on growth and yield of Bt. cotton during 2019–20 at the Soil and Water Management Research Farm, Navsari. The experiment was laid out in a randomised block design with four replications and ten treatments. The results revealed that application of 100% NPK through fertigation (T1) recorded significantly higher plant height, dry matter accumulation, number of sympodial branches/plant, number of bolls/plant, cotton weight per plant, seed cotton yield and stalk yield, but it remained at par with 100% N & K through fertigation with 100% P applied as basal (T2), 100% N through fertigation with 100% P & K applied as basal (T3), 80% NPK through fertigation (T4), 80% N & K through fertigation with 80% P applied as basal (T5) and 80% N through fertigation with 80% P & K applied as basal (T6). Lower growth, yield attributes, and yield were recorded under 80% N fertigation with 80% P and K applied as basal (T9). Boll weight did not remarkably vary under different levels of fertigation.