Vol. 11, Issue 12 (2022)

Cyclopia is a rare congenital anomaly and most severe form of holoprosencephaly, characterised by the single or fusion eye, microcephaly, absence of a nose, a proboscis above the eye. Most such embryos are either naturally aborted or are stillborn on delivery. In the present case a two year old doe gave birth to a dead male kid weighing about 2.45 kg had the features small and elongated head with single eyeball and absence of skeletal structure of the nose. The lower jaw was longer than the upper jaw with protrusion of tongue giving flat face form. The absence of nasal cavity and presence of a rudimentary proboscis above the pseudo-orbit provides typical Cyclops appearance. The causes of cyclopia are not well understood and it may be due to influence of genetic and environmental factors. At present cyclopia is not preventable and there is no treatment available. But in future genetic evaluations of the dam and sire of a defective fetus and analysis of other environmental factors leading to the cyclopia condition may help in prediction and control of this condition.