Vol. 11, Issue 12 (2022)

Author(s):
Khatri Shweta P, Suthar BN, Desai RV, Nakashi HC and Sindhi PI

Abstract:
The current study to evaluate the chemo-sterilization effects of single intratesticular injection of calcium chloride (CaCl₂) in Wistar rats was undertaken at the Department of Veterinary Gynaecology and Obstetrics. Total of 18 mature male Wistar rats were randomly divided into three groups (n=6) as control (intratesticular injection of normal saline), T₁ (intratesticular injection of 20% CaCl¬2 solution at the dose rate of 0.1 ml/100 gram body weight) and T₂ (same as T₁ group, but with additional subcutaneous injection of meloxicam at the dose rate of 2 mg/kg body weight for three days). The rats were observed for changes in ultrasonographic measurement of testicle length, width and echogenicity. Ultrasonographic examination of testis for length, width and echogenicity on day 0, 5, 10, 20 and 30, revealed that length remained unchanged in the control group, but a gradual and significant (p < 0.01) reduction was recorded in T₁ and T₂ groups. The mean values of width of testis remained unchanged in control group but there was significant (p < 0.01) decrease in the testicular width at day 30 in T₁ and T₂ groups compared to control group. Echogenicity showed an increase and then significantly reduced trend over a period. On day 30 anechoic testes was observed in T₁ and T₂ groups, while the echogenicity remained unchanged in the testicles of control group rats.