Vol. 11, Issue 12 (2022)

Author(s):
R Edith, BR Latha and M Balagangatharathilagar

Abstract:
Screening of plants for anthelmintic property is a promising alternative for routine chemical anthelmintics drugs to reduce the problem of anthelmintic resistance and to avoid drug residues in meat and milk products. Haemonchus contortus, the stomach worm of sheep, causing severe economic loss to the Indian farmers in terms of decreased body weight gain and reproduction. The leaves of Pithecellobium dulce (Manila tamarind), Memordica charantia (Bitter guard) and Carica papaya (Papaya) In the present the aqueous leaf extracts of P. dulce, M. charantia and C. papaya were screened for their anthelmintic effects by in-vitro Egg hatch assay and Larval development inhibition assay at 0.5, 1, 2, and 5 percent concentrations in comparison with thiabendazole. P. dulce leaf aqueous extracts showed inhibitory effect on egg hatching though there was initiation of embryonation at first 24 hrs of incubation. However, no degeneration of egg shell was observed. M. charantia leaf aqueous extracts showed hatching and immediate mortality of all hatched out larvae at all concentrations. Aqueous C. papaya leaf extracts of showed inhibition of egg hatching and degeneration of eggs with varying percentages at all concentrations.