Vol. 12, Issue 3 (2023)

Author(s):
T Sathyabama, A Kirubakaran and P Selvaraj

Abstract:
The current study was undertaken to explore the effect of silver nano particle as a topical bactericidal agent. Silver nano particle (AgNP) was synthesized by chemical reduction method and characterized by Transmission Electron Microscope (TEM). The bactericidal activity of AgNP was determined using the disc, gauze and well diffusion method against common clinical pathogenic bacteria. The highest bactericidal effect was observed at the concentration of 40 µL as a maximum diameter of zone of inhibition (mm) and the observed results showed that the AgNPs have potent bactericidal activity against both gram positive and gram negative bacteria. The present study indicated that AgNP can effectively be used as an alternate to antibiotic topical agent, when antibiotic resistance is suspected.