Vol. 12, Issue 3 (2023)

Author(s):
Anil Kewat, Ajit Pratap Singh, Shashi Kant Mahajan, Madhuri Sharma, Sona Dubey, Priti Mishra, Shiv Mohan Singh, Priyanka Gautam, Satyendra Katara and Shivani Pathak

Abstract:
Osteoporosis is a common skeletal disorder characterized by low bone mass and skeletal micro-architectural deterioration, increased risk of fracture and associated co-morbidities most prevalent in the elderly. Due to an increasingly aging population, osteoporosis has become a significant health issue requiring innovative disease management. Proteins are essential for healthy bone, protein intake plays a considerable role in both bone development and bone maintenance. The most abundant sources of collagen are land-based animals, such as cows and pigs. However, the extraction of collagen from non-mammalian sources such as fish has strongly influenced current society due to some religious and disease transmission issues. Many studies have dealt with collagen extraction and anti-osteoporotic properties from fish wastes. Collagen-derived products such as gelatin or collagen hydrolysates are well acknowledged for their safety from a nutritional point of view. In this manuscript, we critically review the evidence from the literature for the effect of fish collagen peptides on bone tissues to determine whether collage peptides may represent a relevant alternative in the design of future nutritional approaches to manage osteoporosis prevention.