Vol. 7, Issue 4 (2018)

Author(s):
Karthik Kotha, Kotinagu Korrapati and Kondal Reddy

Abstract:
The effect of supplementation of encapsulated Bifidobacterium bifidum 235 with prebiotics in milk fat rich high cholesterol diet on serum profile of experimental rats was studied for 45 days. The serum samples for estimation of total cholesterol were analysed at 15 days interval. The total cholesterol (9.40%) of rats feed on high cholesterol diet supplemented with encapsulated synbiotic were significantly lower than all the other groups. There was further reduction in total cholesterol (9.73%) has observed in rats fed with high cholesterol diet supplemented with encapsulated Bifidobacterium bifidum 235 which may be due to encapsulation has protected organisms from adverse conditions of gastro intestinal tract, relatively lesser in total cholesterol (4.80%) was seen rats fed with high cholesterol diet with non encapsulated synbiotic may be due to feeding of non encapsulated synbiotic. In rats fed with high cholesterol diet with non encapsulated Bifidobacterium bifidum 235 there was least reduction in total cholesterol (2.89%) when compared to the group fed only on control diet.