Vol. 7, Issue 4 (2018)

Author(s):
Tkachuk NP

Abstract:
The effectiveness of pramipexole use in patients with restless leg syndrome due to diabetic polyneuropathy has been studied by means of immobilization test. The study involved 123 patients with type II diabetes mellitus, complicated by diabetic polyneuropathy. 32 patients were diagnosed with restless leg syndrome on the basis of principal diagnostic criteria as well as prior ineffective treatment with gabapentin. Patients were interviewed according to the international scale of restless leg syndrome. Immobilization test advanced with turns-amplitude analysis was used to objectivate the manifestations and define the severity of the disease. The study of the dynamics of movement indices revealed that on the 4th week of treatment the number of movements decreased and was 16.51±0.34 versus 44.63±0.45 before treatment (p<0.05). Conducting turns-amplitude analysis made it possible to differentiate the causes of pathologic afferentation of lower limbs in patients with restless leg syndrome comorbid with diabetic polyneuropathy.