Vol. 12, Issue 3 (2023)

Author(s):
Prerna Sood and Manoj Kumar Singh

Abstract:
Nanoparticles (NPs) are now routinely used in a variety of fields, including consumer products pharmaceuticals and medicine. Due to the ease of synthesis and flexibility of surface functionalization, gold nanoparticles (AuNPs) have been extensively used in the practice and in advancement of chemistry, biology and medicine. AuNPs can be used to impact cellular physiological processes like proliferation and differentiation, according to recent studies. In this study, buffalo ovarian cells were co-cultured with two sizes of AuNPs (10 and 100 nm) at three different concentrations. In the experiment group, ovarian cells co-cultured with 100 nm gold nanoparticles had more impact on cytotoxicity of cells as compared with cells treated with 10 nm gold nanoparticles. Gold nanoparticles were found to be harmful to ovarian cells at concentrations 100 nm or more than 100 nm.