Vol. 7, Issue 4 (2018)

Author(s):
Utsha Chakma, Tushar Ahmed Shishir, Maliha Tasnim Deeba, Md Nasiful Islam, Zarif Morshed, Rezowana Islam and Kazi Nuruddin Al Masud

Abstract:
Medicinal plants are the key source of medicines in human life. This present study was aimed to evaluate the anti-microbial and cytotoxic activity of the methanolic extract of Persicaria glabra whole plant. The pharmacognostic analysis of Persicaria glabra has been useful to identify authentic compounds and recognize isolates. The methanolic whole plant extract of Persicaria glabra showed antimicrobial activity against different bacterial strains, including gram negative, gram positive, and three fungal strains using the agar diffusion method. The methanolic extract showed broad spectrum antimicrobial activity Aspergillus niger. Methanol extract showed high cytotoxicity value with low IC50 values. Antimicrobial studies have shown that the whole plant of Persicaria glabra has antimicrobial activity against selected pathogens. The brine shrimp lethality test is an excellent predictive tool for the toxic potential of plant extracts in humans.