Vol. 12, Issue 5 (2023)

Methods: The chicks were randomly divided into three groups of each 50 birds. The chicks were vaccinated on 21^st day with live ND LaSota vaccine mixed with collagen beads (NDV-CG-BDs) were administrated though oral routein group I. In group II, the birds were vaccinated on 21 days of age with the same batch of live lentogenic ND LaSota vaccine through oral route. In group 3, no vaccines were given throughout the study. Haemagglutination inhibition (HI) test was used to assess the humoral antibody response for Newcastle disease. There were no untoward reactions in vaccinated birds throughout the study period of 45 days.

Result: Collagen beads for Newcastle disease vaccine at the dose rate of one to two beads orally was dispensed to one month old Aseel chickens and 0, 7, 14, 28, 45 and 62 days post vaccination blood sample in filter paper was collected for titre estimation using Haemagglutination inhibition test (HI). Oral delivery of commercial lasota vaccine mixed with collagen beads in the present study elicited protective antibody titre for 45 days without interfering production and weight gain. The present study concluded that, the poultry farmers can easily adopt the technology at the farm site and control the Newcastle disease in backyard poultry.