Vol. 12, Issue 5 (2023)

Author(s):
Laltlankimi Varte, Ravindran R, Amrit Gogi, Malsawmkima, N Bhumapati Devi, Neithono Kuotsu, Sashitola Ozukum and Keneisezo Kuotsu

Abstract:
One of the main reasons for the decline in the swine population is reproductive failure. Porcine circovirus (PCV), the cause of PCV2-related reproductive failure, is characterised by acute systemic sickness in the dam, abortion, mummified foetuses, stillbirths, or weak-born piglets. The virus primarily attacks lymphoid tissues, causing lymphoid depletion and immunosuppression in pigs. The purpose of this study was to investigate the pathology and molecular diagnosis of porcine circovirus-2-associated reproductive failure in Zovawk. The PCV was detected using primers to amplify the ORF2 region. The most common gross lesions observed in the study were hydrothorax and or ascities, an enlarged and congested liver, enlarged lymph nodes with mild congestion, and pneumonic lungs. Renomegaly and splenomegaly were also observed. Histopathologically, the lungs showed interstitial pneumonia, loss of hepatocytes, hydropic degeneration, and mononuclear infiltration in the liver. The kidneys showed hydropic degeneration of the tubular epithelial cells with vascular congestion and haemorrhages in the inter-tubular spaces. The spleen revealed mild to severe lymphoid depletion.