Vol. 12, Issue 5 (2023)

Author(s):
Debolina Dattaray, Tushar Kanta Garnaik, Raja Loganathan, Tapan Kumar Mandal, Tapas Kumar Sar and Manisha Chhikara

Abstract:
Imidacloprid is a member of the neonicotinoids insecticide group and the systemic accumulation in food acts as a major source of exposure. The indubitable need for investigations of imidacloprid toxicity in non-target species is required to understand the implications on food chain and ultimately human health. In the present study, we aimed to investigate the subacute effect of imidacloprid on haemato-biochemical parameters of black Bengal goats. In this experiment, 20 healthy black Bengal goats were divided into two groups, Group A: 4 goats and group B:16 goats further subdivided into groups I (DI) and II (DII)of 8 animals each which were administered technical grade imidacloprid as oral gavage for 28 days at minimum toxic dose (45 mg/kg bw/d) and maximum non-toxic dose (25 mg/kg bw/d). Out of 8 animals, 4 were sacrificed on the 29^th day of the experiment, and the remaining 4 were sacrificed at the end of the withdrawal period of 15 days. Blood and serum samples were collected on days 0, 14th, and 28th day respectively, and hemogram, and biochemical parameters were observed. No significant change in the hemogram but slight increase in serum protein, AST, and ALT levels observed which could be corroborated with the tissue biochemical levels and pathological changes in the liver and kidney tissue. The findings of the study were somewhat similar to the previously documented literature and contradicted at a few parameters. Thus, the results of the experiment indicate that imidacloprid had a minimum toxic effect at the given dose.