Vol. 12, Issue 5 (2023)

Author(s):
Payghan PS, Bhojne GR, Dhoot VM, Panchbhai CG, Kolte SW, Tembhurne PA and Shrideeksha

Abstract:
The canine hookworm, Ancylostoma caninum is the most prevalent gastrointestinal nematode parasite of dogs throughout the globe and a common cause of diarrhoea in dogs. A study was carried out to assess haemato-biochemical response and anthelmintic therapy in diarrhoeic dogs diagnosed with Ancylostomosis at Veterinary Clinical Complex, Nagpur Veterinary College, Nagpur. A total of 213 dogs with symptom of diarrhoea were screened of which 51 were found positive for Ancylostoma spp. infection. Therapeutic management was carried out in three treatment groups comprising 12 dogs in each group. Group I was treated with Pyrantel pamoate (10mg/kg, PO, single dose), Group II was treated with Fenbendazole (50mg/kg, PO, for 3 consecutive days) and Group III was treated with Doramectin (0.4 mg/kg, SC, single dose). Therapeutic response was assessed in terms of reduction in EPG on 7^th and 15^th day post-treatment. All three treatment groups showed a complete reduction of egg burden in faeces on day 7^th and day 15^th post-treatment. The study revealed a decrease in Haemoglobin (Hb), packed cell volume (PCV), total erythrocyte count (TEC) (microcytic hypochromic type of anaemia), eosinophilia, hypoproteinaemia, hypoalbuminemia, hypoglobulinemia and decreased blood urea nitrogen in Ancylostoma infected dogs. Improvement in haemato-biochemical parameters were observed following treatment.