Vol. 12, Issue 7 (2023)

Author(s):
K Sudha, D Baskaran and Rita Narayanan

Abstract:
The present study was undertaken to evaluate in vitro antioxidant, antidiabetic and anti-lipase activities of selected fruits viz., Amla, Grape, Jamun and Kiwi. Antioxidant activity of fruit extracts were assessed by DPPH and SOD methods. In DPPH method, the highest antioxidant activity was observed in aqueous extract of jamun (92.333±0.71), followed by kiwi, grape and amla (86.500±0.34) whereas in SOD method, the highest antioxidant activity was found in aqueous extract of amla (94.886±0.49), followed by grape, jamun and kiwi fruit (81.451±0.70). In vitro antidiabetic activity of different fruit extract was observed by starch-agar gel diffusion method, it was found that the highest inhibitory activity of alpha amylase was observed in jamun (98.333±1.05), followed by grape, kiwi and amla (70.965±0.14) whereas, the highest inhibitory activity of alpha glucosidase was found in amla (94.420±0.10) followed by grape, jamun, and kiwi fruit (50.778±0.17). Anti-lipase activity of aqueous fruit extract was assessed by rhodamine agar plate method, the highest inhibitory activity was exhibited by aqueous extract of jamun (94.675±0.11), followed by kiwi, amla and grape (51.511±0.38). In pancreatic lipase inhibition method, maximum inhibitory activity was found in jamun (67.751±0.09), followed by kiwi, grape, and amla (31.760±0.35). In the study, fruit extracts proved to have therapeutic effects as antioxidant, antidiabetic and anti-lipase properties were found in fruit extracts.