Vol. 7, Issue 6 (2018)

Author(s):
Verma Pratibha, Dhyani Archana and Juyal Divya

Abstract:
The microsponge are used to deliver drug to chronopharmacology for improve the drug bioavailability and the potency of active drug. Chronopharmacology is the investigative science that elucidates the biological rhythm dependencies of medication. It is useful to solve problems of drug optimization (to enhance the desired efficiencies or to reduce its undesired effects). The effectiveness and toxicity of many drugs vary depending on dosing time associated with 24 hours rhythm of biochemical, physiological and behavioural process under the control of circadian clock this chronopharmacological process is partial not only by pharmacokinetics but also pharmacodynamics of treament.