Vol. 12, Issue 8 (2023)

Author(s):
Dr. C Vinaya Sree, Dr. Radha Krishna Pulikanti, Dr. Bommu Swathi, Dr. Gurram Srinivas and Dr. Bora Swathi

Abstract:
The growth factors and their respective signalling pathways affect not only the embryonic development but also the adult reproductive tract function. To list a few, they are Insulin-like growth factor (IGF), Vascular endothelial growth factor (VEGF), transforming growth factor-β (TGF-β), wingless-type MMTV integration site (WNT), Hedgehog, epidermal growth factor (EGF), phosphatidylinositol 3-kinase (PI3K), Hippo, and Notch. This article focusses on the role of IGF and VEGF and their pathways as to how they regulate the female reproduction.