Vol. 7, Issue 8 (2018)

Author(s):
Dharmaceelan S, Ramakrishnan KS, Senthilkumar S, Vijayakumar G and Rajendran N

Abstract:
Clinical study was conducted to access the cardiovascular effect of buprenorphine and butorphanol in 18 female cats anaesthetized with midazolam-ketamine- isoflurane. The cats were divided in to three Groups. In Group I, anaesthesia was induced by midazolam (@0.3mg/kg) ketamine (11mg/kg) mixture. In Group II and Group III cats, butorphanol and buprenorphine were administered @ 0.4 mg/kg and 0.01 mg/kg, 15 minutes prior to induction as in Group I and maintained with isoflurane. Pulse rate, Respiration rate, saturation of peripheral oxygen (SPO₂), inspired fraction of oxygen (FiO₂), end tidal oxygen (ETO₂), inspired fraction of carbon dioxide (ETCO₂), end tidal carbon dioxide and electrocardiography were recorded. A significant (p<0.05) increase in pulse rate during 5, 10 and 30th min. after induction in group III was observed. Statistical comparison revealed no significant change in the FiO₂, ETO₂ and ETCO_2. No life threatening cardiovascular emergencies were noticed during the ECG study.