Vol. 13, Issue 3 (2024)

Spondia mombi belonging to the Anacardiaceae family has demonstrated efficacy in treating inflammatory conditions, wounds, and infections. Found commonly in Africa, Americas and Asia, its leaf extract was tested for their antiaflatoxin, anti-inflammatory and biosafety properties. A thin layer chromatographic (TLC) technique was employed to assess aflatoxin levels in Aspergillus flavus, Aspergillus versicolor and Fusarium oxysporum. The inhibition of aflatoxin increased with higher concentrations of Spondia mombi leaf extract, with aflatoxin B1 being completely inhibited at 300mg/ml concentration. Additionally, the plant extract showed significant protection against hemolysis, particularly at higher concentrations and no hemolysis was observed in the absence of aflatoxin. This study highlights the potent antiaflatoxin, anti-inflammatory and biosafety of properties of Spondia mombi leaf extract, suggesting potential for further exploration of plant-based remedies for various medical conditions.