Vol. 13, Issue 5 (2024)

Electronics, minerals, geosciences, materials science, medicines, and other fields saw rapid growth due to the structural knowledge derived from crystallographic research. Understanding the structure of active pharmaceutical ingredients (APIs) is necessary for the synthesis of novel chemical entities intended for use in the creation of new drugs as well as for the rational design of drugs. In the last twenty years, X-ray crystallography has been essential to the use of X-rays to examine crystals is known as X-ray crystallography (XRC). X-ray crystallography (XRC) is the principal technique used to visualize and discover the detailed structure of molecules, particularly those related to living systems. The process involves subjecting a well-organized crystal of a substance to X-rays, and then obtaining the structural information from the spots that are created on a film as a result of this impact. The structure of the majority of milk proteins has been found via X-ray crystallography, which has been widely and significantly utilized in the analysis of liquid milk, milk powders, milk stones, polymorphism of milk fat, and linking the structure of these proteins with potential roles. X-ray crystallography helps analyze the active pharmaceutical ingredients (APIs) in pharma industries, it also used in Nano science, Forensic sciences, Electronic device materials making. Protein stracture analysis.