Vol. 7, Issue 12 (2018)

Author(s):
Vijay Kumar, Meera Cholera, Tukaram Dudhamal, Mukeshkumar and Nariya

Abstract:
Stability studies ensuring the maintenance of product quality, safety and efficacy throughout the shelf life are considered as pre-requisite for the acceptance and approval of any pharmaceutical product. The paste of Katupila leaves has been described by the medico-ethno botanist as a wonderful drug for the treatment of wound. Microbial contamination should be taken care of to increase shelf life of any formulation. Pastes of Katupila leaves powder in two media i.e. water and sesame oil were prepared and studied to check microbial contamination at different climatic conditions at different time interval. To analyze mycological findings and presence of microorganisms in paste, wet mount test and Gram stain test where applied respectively. At the end of the study, sample of Katupila paste in any media did not show any kind of microbial contamination with the changing in climatic conditions.