Vol. 8, Issue 2 (2019)

Author(s):
Randhir Singh, SNS Randhawa and CS Randhawa

Abstract:
Twenty one buffaloes were divided equally into three groups of seven animals each based on results of metabolic profile screening i.e., Group I: Healthy {Pre-partum Non esterified fatty acid (NEFA) levels at close up dry stage (CUD) ≤0.4mmol/L}; Group II (positive control): Pre-partum NEFA levels at CUD stage ≥0.4mmol/L and Group III: NEFA levels at CUD stage ≥0.4mmol/L and supplemented with oral propylene glycol @250 ml once a day for 5 days. Sampling was again done at fresh stage of transition period to evaluate the efficacy of PG as a prophylactic measure to prevent development of SCK in transition buffaloes.Results revealed significant increase in mean PCV percentage from 37.87±1.48% to 42.79±1.21% after propylene glycol administration in group III. Beta hydroxyl butyric acid (BHBA) levels increased significantly in group II from CUD (0.76±0.03 mmol/L) to fresh stage (1.49±0.03 mmol/L) and were significantly higher than PG supplemented group (0.90±0.12 mmol/L) at fresh stage. Non esterified fatty acid (NEFA) recorded non significant increase and decrease in group II and PG supplemented group, respectively. Five out of seven buffaloes, which were administered PG @ 250 ml /day for 5 days orally, crossed transition period uneventfully, whereas, only two buffaloes developed SCK after parturition at fresh stage. All the seven buffaloes in group II (positive control) developed SCK after parturition.