Vol. 8, Issue 6 (2019)

Author(s):
Sreelakshmi K, Vinaykumar R Kadibagil and Sudhakar Bhat

Abstract:
Now a days gastro intestinal problems are increasing day by day.10% of world population are affected. It is caused due to etiology of H pylori infection, utilization of anti inflammatory drugs, cigarette smoking, chronic alcohol consumption, stress and altered prostaglandin synthesis, E metabolism. The symptoms of gastric ulcer almost resembles to that of Amlapitta. There are many formulations are mentioned for the treatment of Amlapitta in Ayurveda classics. There are different dosage forms mentioned in the treatment of amlapitta like Churna, Kwatha, Asavaarishta, Rasayoga, Arka. Arka kalpana is one of the potent kalpana mentioned by arka prakasha. Amlapittaghna Arka is mentioned for treatment of Amlapittta in Arka Prakash which contains Guduci (Tinospora cordifolia), Nimba (Azadiaracta indica), Patola (Trichosanthus dioca) as ingredients. Recent researches done on individual drugs proved anti-ulcer activity of the three drugs. Gastro protective activity of Amlapittaghna Arka was assessed by aspirin induced gastric ulcer on wistar albino rats in experimental study. Biochemical parameters like increase in gastric pH, volume, total acidity, carbohydrate, decrease in free acidity, ulcer index, protein content was observed.