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Journal code(s)
- E-ISSN Number: 2277-7695
- P-ISSN Number: 2349-8242
- CODEN Code: PIHNBQ
- ZDB-Number: 2663038-2
- IC Journal ID: 7725
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Vol. 8, Issue 9 (2019)
Effect of zidovudine on fetal length & fetal weight of developing mice
Author(s):
Amit Kumar Nayak, Anand Mishra, Krishna Pandey, Amrita Singh and Kapil Kumar Malviya
Amit Kumar Nayak, Anand Mishra, Krishna Pandey, Amrita Singh and Kapil Kumar Malviya
Abstract:
Introduction: Zidovudine was the first antiretroviral agent to demonstrate clinical efficacy in patients infected with HIV. Its currently widely used as a part of highly active antiretroviral therapy. The current study is done to see the effect of zidovudine on fetal length & fetal weight of swiss albino mice.
Introduction: Zidovudine was the first antiretroviral agent to demonstrate clinical efficacy in patients infected with HIV. Its currently widely used as a part of highly active antiretroviral therapy. The current study is done to see the effect of zidovudine on fetal length & fetal weight of swiss albino mice.
Material & method: Zidovudine was given to mice in doses of 50,100 & 150 mg/kgbw. Length & weight of fetuses were measured.
Result: Dose dependent decrease in fetal length & fetal weight was observed.
Conclusion: In this study we concluded that zidovudine is teratogenic to developing mice & should be cautiously used in clinical cases.
Pages: 423-425 | 263 Views 48 Downloads
How to cite this article:
Amit Kumar Nayak, Anand Mishra, Krishna Pandey, Amrita Singh, Kapil Kumar Malviya. Effect of zidovudine on fetal length & fetal weight of developing mice. Pharma Innovation 2019;8(9):423-425.
Journal code(s)
- E-ISSN Number: 2277-7695
- P-ISSN Number: 2349-8242
- CODEN Code: PIHNBQ
- ZDB-Number: 2663038-2
- IC Journal ID: 7725
Main Menu
Special Issue
Copyright Form
Identifier
The Pharma Innovation Journal
