Vol. 9, Issue 1 (2020)

Author(s):
Dr. Majid Shafi Kawoosa and Shabia Khan

Abstract:
This experimental work was conducted to study the pathomorphological changes of Nimesulide induced toxicity in Japanese Quails. A total number of 100 healthy Japanese quails were reared up to two weeks of age and then divided into four major groups i.e. Control (C) group and the three Treatment groups namely N1, N2 and N3 respectively. Experiment was carried out on 100 birds out of which 25 birds were kept in each group. The birds in control group received normal starter feed without any medicine and the drug was given with feed @ 10, 20, and 30 mg /kg body weight to the birds of N1, N2 and N3 groups for 15 days. The intoxicated birds revealed nephropathy and depletion of lymphoid tissue from the lymphoid organ which were suggestive of immunosuppressive effect of Nimusilide in intoxicated birds.