Vol. 9, Issue 2 (2020)

Author(s):
Ananya Bhowmick, Prosenjit Mukherjee, Rahaman Mehedi Mamud, Monit Paul, Anusree Raha and Anindya Bagchi

Abstract:
Haemostasis is the process of forming clots in the walls of damaged blood vessels to prevent abnormal bleeding and to maintain intravascular blood in a fluid state. There is an increasing need to source for pharmacological and medicinal materials from plant source. The present study comprises the possible coagulation effect of Acalypha leaf chloroform and methanol extract having in vitro coagulant activity by using blood samples of poultry bird. In vitro coagulation effect of Acalypha leaf extract in different concentrations were examined in the blood samples of poultry bird by measuring Prothrombin Time (PT) in respect of the standard drug. The extracts were found to have coagulation activity and significantly prothrombin time in a dose-dependent manner. The principle involved in this extract is in different concentrations for the clot formation and decrease prothrombin time. This is also a subject for further studies on efficacy and safety, it also can be used in the future as a supplementary coagulant agent in blood vessels.