Vol. 10, Issue 9 (2021)

Author(s):
Dabholkar Akshay Rajkumar, Bibu John Kariyil, Shashikant P Vaidya, Suja Rani S, Nisha AR and Dhanush Krishna B

Abstract:
Carbosulfan belonging to carbamate class of insecticides are commonly used in agricultural practices for soil, foliar and seed treatment. There is a paucity of data about the carcinogenic effects of carbosulfan. Hence the present study was envisaged to evaluate the carcinogenic effects of carbosulfan using cell transformation assay in BALB/c 3T3 clone A31 cell line. Carbosulfan treatment at 50 µg/mL showed time dependent transformation in BALB/c 3T3 clone A31 cells revealing its carcinogenic potential. The data thus obtained could be useful in elucidating the various health hazards in humans and animals due to the environmental exposure to carbosulfan.