Vol. 10, Issue 12 (2021)

Author(s):
B Sravanthi and N Lakxmi Bhavani

Abstract:
Indian medicinal plants used in the Ayurvedic traditional system to treat diabetes are a valuable source of novel anti-diabetic agents. Averrhoa carambola L. belonging to the family Oxalidaceae, traditionally known as “kamrakh” and commonly known as star fruit because of its peculiar shape. Fruits and leaves are used widely in Ayurveda preparations for diabetic and general debility. The aim of this work was to evaluate the toxicity and α-amylase inhibitory activities of the crude fruit extracts of A. carambola in petroleum ether, chloroform, ethyl acetate, acetone and methanol. In vitro α-amylase studies result reveled the significant inhibition of α -amylase activity in dose depend manner. Among all the extracts methanolic fruit extract showed maximum of 72% of Inhibition of α- Amylase which was similar to that of acarbose (standard) with 76% of Inhibition. Further in vivo study is necessary to confirm the antidibetic activity of star fruit.