Vol. 11, Special Issue 1 (2022)

Author(s):
Sunil Hajare, Ranjit Suresh Ingole, Mahesh Kumar Vitthal Ingawale, Vivek Borekar, David Kumar, Ravikanth Kotagiri and Bhaskar Ganguly

Abstract:
Achieving and maintaining egg quality and production levels is essential for a successful poultry layer enterprise. Layer egg quality and production levels are widely affected by a variety of factors, including inadequate management, nutritional status, and various diseases. AV/EFE/19 is a phytogenic herbal egg quality enhancer that helps to achieve optimum egg quality in layers. A study was conducted to assess the acute oral toxicity potential of AV/EFE/19 (M/s Ayurvet Limited, India) according to OECD 423 recommendations. Nine adult female Swiss albino mice, weighing 24-29 g, were used for the study. Following the oral administration of AV/EFE/19, the animals were observed for the manifestation of toxic effects and mortality. Toxicity was evaluated on the basis of changes in body weight, signs of toxicity, histology of vital organs (heart, liver, kidney, and lungs), and blood biochemical parameters (AST, ALT, ALP and creatinine). No toxic effects or mortalities were noticed until day 14 and AV/EFE/19 was found safe for oral consumption.