Vol. 11, Special Issue 3 (2022)

Author(s):
Raghavendra Prasad Mishra, Saurabh Singh, Mohd Akil, Pratipal Singh Kaurav and KM Prachi Gautam

Abstract:
Dermatophytosis is a highly zoonotic and group of cutaneous diseases widely distributed in human and animals including rabbits. It causes serious infection in some human cases and economic losses in farm animals. The primary aim of this study is to conduct an investigation of potential risk factors causing dermatophytosis and efficacy of common therapeutic drugs against dermatophytosis. During the present study, a total of 105 rabbits were taken out of which 63 rabbits were found positive for dermatophytosis all the positive cases further processed for the testing of effectiveness of antifungal drugs as individual and in combination form. In the present study risk factors like diet with vitamin and mineral supplement and deworming of animal was significant effect, other parameters like sex, age, body weight and ectoparasite was not significant effect in the infection of dermatophytosis in rabbits. Among the drugs taken for testing in the present study the most effective drugs combination was ketoconazole orally @ 10-15 mg/kg/day with 2.5% lime sulphur solution (dip twice in a week) which completely cured the infected rabbits about 92.30% (12/13) within 2-3 weeks of treatment and other drugs also showed good ability against infection. Due to its zoonotic point of view early diagnosis and treatment should be performed.