Vol. 11, Special Issue 3 (2022)

Author(s):
Suman Yadav, Sarvan Kumar, Raghvendra Raman Mishra and Ratan Shankar Mishra

Abstract:
Infant jaundice, an important pathological condition in the first week of infants’ life is characterized by hyperbilirubinemia with clinically manifestations of yellowish discoloration of visible mucous membrane, skin and sclera of the eye. In a present study, total of one hundred fifteen patient samples registered for serum bilirubin concentration diagnosis were analysed with comparison between pre-hepatic and post hepatic infant jaundice using concentration of unconjugated/indirect serum bilirubin and conjugated/direct serum bilirubin method. Data analysis revealed that 89.56 per cent of samples were diagnosed for both pre & post hepatic jaundice, whereas only 4.34 per cent and 5.21 per cent for pre-hepatic and post hepatic jaundice, respectively. During serum biochemical study, it was also found that there was significant (P≤0.05) increase in the mean concentration of total serum bilirubin & conjugated serum bilirubin in patients reported for infant jaundice, whereas there was significant (P≤0.05) decrease in the mean values of unconjugated bilirubin when compared with the corresponding referral values of serum bilirubin.