Vol. 11, Special Issue 3 (2022)

Author(s):
Dr. V Pavani, Dr. M Lakshman, Dr. D Madhuri and Dr. A Gopalareddy

Abstract:
Lead (Pb), a ubiquitous metal, is one of the most abundant elements present on earth. Thiram (Tetramethyl thiuram disulfide – TMTD) is a systemic fungicide and seed protectant. Both had synergistic cytotoxicity. The experiment was designed to study the pathology of lead acetate, tetramethyl thiuram disulfide and its combination induced toxic effects in broilers. hundred day old broiler chicks (Vencobb strain) weighing 45-50g were procured from M/S Venkateshwara Hatcheries Pvt. Ltd., Hyderabad. They were divided into four groups, 25chicks in each group. The group 1 (control) fed with basal diet, group 2 (lead acetate) at the rate of 300 ppm per day, group 3 (tetramethyl thiuram disulfide) at the rate of 60 ppm per day and group 4 birds were fed with combination of lead acetate and tetramethyl thiuram disulfide with same dose. The duration of experiment for 5 weeks and the age of the birds were 6 weeks (first week for acclimatization). Average body weights were recorded at weekly intervals (1-6 weeks). A significant (P<0.05) reduction in the body weights were recorded in groups 2, 3 and 4 over group 1 birds.