Vol. 11, Special Issue 4 (2022)

Author(s):
Dishant Aggarwal, Vinod Dumka, Simratpal Saini and Rashmi Sagar Bhullar

Abstract:
Different concentration of hydro-alcoholic leaf extracts of Aegle marmelos and Justicia zeylanica were investigated for in vitro antioxidant (at concentration of 10-1000 µg/ml) and antibacterial ( at concentration of 100, 150, 200 and 500 mg/ml) activity. Further, in vivo muscle relaxant and grip strength activities (at concentration of 100 and 200 mg/ml) were also investigated. Both leaf extracts show antioxidant activity (such as total phenolic content, DPPH, ABTS, FRAP assay) as compared to standard but J. zeylanica showed more antioxidant potential as compared to A. marmelos. Both the extract show antibacterial activity against different bacterial strains (S. aureus, B. cereus, L. monocytogenes, E. coli, S. typhimurium, Y. enterocolitica, V. cholera and S. flexneri). However, present study revealed no muscle relaxant and grip strength activity of hydro-alcoholic leaf extracts of A. marmelos and J. zeylanica as when compared to the control group.