Vol. 11, Special Issue 7 (2022)

Author(s):
P Sarkar, CK Ghosh, K Kumar, A Shee, S Basu, S Kumar and A Roy

Abstract:
Pyometra is a common reproductive disorder that affects more than one third populations of bitches over 7 years of age in which physiological effects of progesterone on the uterus play a major role. Ovariohysterectomy is the usual treatment for pyometra. The main advantage of ovariohysterectomy is both curative and preventive for recurrence of pyometra over medicinal therapy. However, surgery is associated with the risk of anaesthesia and offers the bitch sterile. Since last 10-12 years, several medical treatments have been suggested to treat both open and closed cervix pyometra. The most useful medical treatment with minimum side effects seems to be administration of mifepristone with additional treatment with low doses of prostaglandin E1 analog (Misoprostol).