Vol. 11, Special Issue 7 (2022)

Author(s):
Dr. RM Gowtham, Dr. M Chandrasekar, Dr. B Gowri, Dr. M Balagangatharathilagar and Dr. S Kavitha

Abstract:
A pet parent presented an Eight years old, intact, male, cross breed dog to the Critical Care unit, Department of Veterinary Clinical Medicine, MVC, Chennai with the history of self medication with Ibuprofen oral tablet (200 mg, daily twice) for three days. After that, the pet was showing progressive weakness, vomiting, melena. At the time of presentation, the pet was recumbent and decreased mental status. Based on the history, clinical signs, hemato- biochemical and urine analysis and ultrasonographic examination, the case was diagnosed as “Ibuprofen induced Acute Kidney Injury”. Treatment was initiated with intravenous fluid therapy (Inj. Ringer’s lactate @ 20 ml/kg), Inj. Ondansetron @ 0.2 mg/kg IV, Inj. Pantoprazole @ 1mg/kg IV, Inj. Amoxicillin potassium clavulanate @ 7.5 mg/ kg and Intravenous lipid emulsion. IV lipid emulsion was administered as a bolus @ 1.5 ml/kg followed by constant rate of infusion @ 0.5 ml/kg/min. The pet’s mental status was improved approximately 3 hrs after initiation of IV lipid emulsion. Activated charcoal was administered orally as a slurry form @ 1g/kg. The pet was recovered uneventfully after 5 days of treatment.