Vol. 11, Special Issue 7 (2022)

Author(s):
Virendra Singh and Raj Kumar

Abstract:
The emergence of antimicrobial resistance in microbes as a result of the indiscriminate and careless use of antibiotics has presented a hitherto unheard-of risk to human civilization. It is challenging to due to bacteria's capacity to acquire resistance against antimicrobial substances, cure bacterial infections. Significant factors in the development of antibiotic resistance include spontaneous evolution, bacterial mutation, and horizontal gene transfer. The clinically available medication is currently ineffective against the antibiotic resistance some bacterial species have evolved. Not only do urgent actions need to be taken to reduce the prophylactic and therapeutic usage of antibiotics, but they also need to be taken to explore for alternate methods of bacterial infection control. Due to an increase in hospital admissions and medicine usage, AMR raises healthcare expenses. It is necessary to take action to reduce the preventive and therapeutic usage of antibiotics. This paper analyses the global antimicrobial resistance situation, causes that encourage its spread, control methods, and constraints.