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Vol. 11, Special Issue 10 (2022)

Comparative efficacy of mucolytic agent (Acetyl cysteine) as nebulizer in conjunction with parenteral antibiotics against bacterial pneumonia in goats

Author(s):
Trupti Suryakant Kattimani, Ravindra BG, Vinay T, Shrikant K, Vivek RK, Basawraj A and Patil NA
Abstract:
In the present study, twenty-four goats suffering from bacterial pneumonia presented to Veterinary Clinical Complex, Veterinary College, Bidar from August 2016 to July 2017 were randomly divided into four groups consisting six in each. Group-1 was treated with Inj. Marbofloxacin @ 2 mg/kg b. wt./day for 5 day, Group-2 treated with Inj. Marbofloxacin @ 2 mg/kg b. wt./day for 5 day with nebulization of mucolytic agent (Acetyl cysteine)-2ml, for 30 mins/day for 3 days, Group-3 treated with Inj. Ceftiofur sodium @ 2 mg/kg b. wt./day for 5 day and Group-4 treated with Inj. Ceftiofur sodium @ 2 mg/kg b. wt./day for 5 day with nebulization of mucolytic agent (Acetyl cysteine)- 2 ml, for 30 mins/day for 3 days. To evaluate the efficacy of drugs alone or in conjunction with mucolytic agent as nebulizer, the blood was collected on day “0 and 5th day of post treatment from all the goats and both haematological and blood gas parameters were critically analysed. The results revealed that faster recovery in pulmonary function was observed in Group-2 (Marbofloxacin and Acetyl cysteine) followed by Group-4, Group-1 and Group-3. Thus, mucolytic agent (Acetyl cysteine) as a nebulizer in conjunction with parenteral antibiotic may be recommended as first line of treatment in bacterial pneumonia in goats.
Pages: 883-889  |  352 Views  216 Downloads
How to cite this article:
Trupti Suryakant Kattimani, Ravindra BG, Vinay T, Shrikant K, Vivek RK, Basawraj A and Patil NA. Comparative efficacy of mucolytic agent (Acetyl cysteine) as nebulizer in conjunction with parenteral antibiotics against bacterial pneumonia in goats. The Pharma Innovation Journal. 2022; 11(10S): 883-889.

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