Vol. 11, Special Issue 10 (2022)

Author(s):
Shumaila Taskeen, Randhir Singh, Vivekanandhan R, Muralikrishna P, Asiya Mushtaq, Sanmeet Kour and Muqtaza Manzoor

Abstract:
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter spp.) are the predominant cause of nosocomial infections all over the world. The bacteria have been popular for their notoriety due to their ability to render the highest class of antibiotics ineffective and have been therefore accredited as the priority pathogens by the World Health Organization (WHO). The remarkable presence of virulence factors along with the development of multi-drug resistance emphasizes an urgent need for development of new therapeutics against these pathogens. This review intends to highlight the critical importance of the ESKAPE pathogens with respect to their potential in development of antimicrobial resistance (AMR).