Vol. 12, Special Issue 7 (2023)

Author(s):
Srinivasa Naik H, Chennappa P and Sailaja N

Abstract:
Mesotheliomas are malignanat tumors arise from the cells of serous lining of body cavities and they may involve all the pleural, pericardial, and peritoneal cavities. Mesotheliomas are uncommon neoplasams in human beings and domestic animals, but are seen most commonly in cattle, horses, dogs and cats. A four years-old Nellore brown ewe suffered with severe respiratory distress for a period of few days and died. Carcass was examined thoroughly and necropsy was carried out and collected samples were processed by routine embedded in paraffin and sections stained with hemotoxylin-eosin. Necropsy of died sheep revealed, 2.5-3 liters of haemorrhagic fluid mixed with little fibrin threads in the thoracic cavity. Very minute to medium, medium to large coalescing whitish to yellowish cauliflower like tumor nodules was noticed on the parietal surface of pleura covered on lungs, pericardium, medial surface of costal ribs and sternum. Proliferation of neoplastic cell arranged in to acinar pattern with papillary projections surrounded infiltrates of inflammatory cells including plasma cells observed in the pleura, lung parenchyma, pericardium and metastatic lesions in the mediastinal lymph nodes. Based on gross and histopathological findings present case diagnosed as pleural and pericardial mesothelioma in a Nellore brown sheep.