Vol. 12, Special Issue 7 (2023)

Author(s):
Jupaka Shashank, K Satish Kumar, VVV Amruth Kumar, B Anil Kumar and M Lakshman

Abstract:
Out of 134 geriatric dogs diagnosed with bacterial lower urinary tract infection (BLUTI) at veterinary clinical complex, college of veterinary science, Rajendranagar, 20 cases with cystitis that were confirmed by history, clinical symptoms, urinalysis, Haemato-biochemical and biomarker estimations, imaging techniques and cultural studies, were selected for therapeutic studies, by randomly dividing them into two groups viz., Group I and II, with 10 dogs in each. Therapeutic regimen for Group I cystitis dogs included Punarnava herbal drug and supportive drugs. The efficacy of treatment regimens was assessed on day 15 by recording remission of clinical symptoms, near normalization of abnormal findings of urinalysis, Haemato-biochemical and biomarkers estimations, disappearance of abnormal ultrasonographical findings and microbiological cure by cultural studies after therapy. Remission in frequency and severity of the clinical signs was noticed from 5^th day of therapy among 5 dogs and complete clinical cure among all the 10 dogs was observed by 15^th day of the therapy. All the abnormal features of the urine samples of all the affected dogs showed marked improvement from day 7 and reached normalcy by 15^th day. Non-significant reduction in haematological parameters like Hb (11.28±0.44g/dl), TEC (5.32±0.28 X10⁶/µl) and PCV (37.24 ± 0.38%) and significantly (p<0.05) elevated in mean TLC (16.74 ±0.45 X10³/µl) on ‘0’ day. Slightly elevated creatinine (1.51±0.19) and BUN (26.58±0.30 mg/dl) values reached to normal reference range by 15^th day of therapy. Microbiological cure on 15^th day of therapy was 100% in this group of dogs with cystitis as urine samples from all the affected dogs was culture negative.