Vol. 12, Special Issue 8 (2023)

CTVT is a distinct, naturally contagious tumour in which the altered tumour cell itself acts as the causal agent and persists in the host as a parasitic allograft. The clinical history, signs, symptoms and cytological markers are frequently sufficient for making a diagnosis, although biopsy and a histological investigation may be required in rare circumstances. With three weekly vincristine sulphate IV injections, the majority of patients are curable. It is challenging to control and necessitates continuing animal birth control in stray dogs due to the disease’s connection to wild and stray dogs. The various advancements around this intriguing tumour, including its biology, diagnostic techniques, and treatment options, are covered in this review.