Vol. 12, Special Issue 9 (2023)

Author(s):
Rajashekar Kamalla and A Shirisha

Abstract:
A six-year-old Pomeranian dog was presented with signs of ataxia, seizures, hypersalivation, and blindness presented to the outpatient department (OPD) of medicine at the Veterinary Clinical Complex (VCC), CVSc, Rajendranagar, Telangana. The dog had previously consumed a large dose of ivermectin (100 mg bolus). It had a high rectal temperature (104.3°F), normal mucus membrane, tachypnoea (70/min), tachycardia (130/min), mydriasis, no menace reflex and no pupillary light reflex, according to the clinical examination. Leucocytosis was found during the haematological examination, however the blood's biochemical profile (BUN: 16.9 mg/dl, creatinine: 1.2 mg/dl, SGPT: 57.3 U/L, SGOT: 34.6 U/L) was within the reference range. Initially, this patient had constant rate infusion therapy at 0.25 ml/kg/h, OD, and isotonic crystalloid solution (0.9% NS) at 30 ml/kg body weight for a total of 10 minutes after receiving 20% lipid emulsion (Intralipid) at 1.5 mL/kg body weight. Neostigmine 0.05 mg/kg b. wt. IV BD, dexamethasone 0.25 to 0.5 mg/kg b. wt. IM BD and ceftriaxone sodium 20 mg/kg b. wt. IV BD repeated every six hours. One oral dose of activated charcoal at 1 g/kg body weight. Five days after ingesting a high dose of ivermectin, the dog's clinical condition returned to normal state. The current case describes the effective treatment of canine ivermectin poisoning.