Vol. 12, Special Issue 10 (2023)

Author(s):
Bhogindra Nath Meher, Dharmendra Kumar, Neelam Tandia, Shailendra Singh, Priya Singh, Vikas Dehariya and Siddharth Wadiwa

Abstract:
The current investigation was carried out on six cattle aged between 1-3 years to investigate haemato-biochemical alterations after receiving ropivacaine and dexmedetomidine as an epidural anaesthesia. The animals were administered with ropivacaine 0.75% at 0.25 mg/kg b.wt. and dexmedetomidine at 5 µg/kg b.wt. in sacrococcygeal space. Haematological parameter such as Haemoglobin percent (Hb%), PCV, TEC and TLC initially decreased and returned near to its baseline value at the end of observation period. Biochemical parameters such as ALT, AST, BUN and CRE increased non-significantly and a significant increase in Glucose value was observed till 90 minutes which returned to its normal base line value at 24 hours. Following epidural administration of ropivacaine combined with dexmedetomidine, temporary and compensatory alterations were seen. Ropivacaine-dexmedetomidine produces early onset of analgesia, profound analgesia, longer duration of analgesia, adequate cardio-respiratory stability and renal function with least effects on haematological and biochemical profiles.