Vol. 12, Special Issue 11 (2023)

Author(s):
Jenita Rani D, Pushpa Rani V and Jannet Philomina D

Abstract:
The aim of this study was to examine the anti-diabetic effect of the plant-encapsulated chitosan nanoparticles which was obtained from the shell and plant samples that are organic waste utilized in the process of preparing a biocompound that can be converted as a bio-product (plant coated chitosan nanoparticles). This biocompound is economic, eco-friendly, cost-effective, non-toxic in nature and also less time consuming for its preparation. The plant-coated chitosan nanoparticles was used for the in vitro α-glucosidase inhibition anti - diabetic assay and in vitro α- amylase inhibition anti - diabetic assay. The anti-diabetic activity of encapsulated chitosan nanoparticles was found to be positive as there was good inhibition of α-glucosidase and α-amylase. Therefore, the plant-encapsulated chitosan nanoparticles can be used in drug delivery systems thereby leading the way to synthesize novel pharmaceutical compounds.