Vol. 12, Special Issue 12 (2023)

Author(s):
Mahavadiya DR, Joshi NH, Vasava Rajesh, Sapra Dharmesh, Rathod Vishal and Vagh Sarman

Abstract:
Present study was taken to investigate effect of supplementation of zinc nanoparticles on disease resistance and haematological parameters in Nile tilapia (Oreochromis niloticus) fry. The experiment was carried out for 60 days. Four experimental animals were prepared namely T₀ (control), T₁ (10 mg/kg), T₂ (20 mg/kg) and T₃ (30 mg/kg). Zinc was selected as a nanoparticle ingredient. The antioxidant chemicals sulfoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and malondialdehyde (MDA) were measured at the end of the experiment along with haematological parameters. Highest SOD, CAT and GPX activity were found in the T₃ treatment (30 mg/kg). Lowest activity of SOD, CAT and GPX were found in T₀ treatment (0 mg/kg). While no significant difference was observed in MDA activity. In blood parameters, highest WBC, haematocrit, platelets were found in T₃ treatment (30 mg/kg) while lowest were found in T₀ treatment (0 mg/kg). RBC count and haemoglobin value did not show any significant difference within treatment. Results indicated that increase in zinc supplementation has shown to increase activity of SOD, CAT, GPX along with showing decreasing MDA level. In the case of haematological parameters, WBC, haematocrit, haemoglobin and platelet counts were increased with increase zinc nanoparticle supplementation. While RBC count did not show significant difference. It can be concluded that overall zinc supplementation increase disease resistance though antioxidant chemicals and also increase haematological parameters. Therefore, to increase the disease resistance T₃ treatment (30 mg/kg) is recommended to increase disease resistance in Nile tilapia (Oreochromis niloticus) fry.