Vol. 12, Special Issue 12 (2023)

Author(s):
K Kannan, G Kesavan, S Madhu Priya, P Senthil Kumar, A Elamaran, V Ranganathan and S Senthil Kumar

Abstract:
The objective of the present study was to investigate the effect of Centella asiatica leaf extract on red blood cells of anaemic goats in vitro. Phytochemical screening of alcoholic extract of Centella asiatica revealed the presence of carbohydrates, phenols, tannins, terpenoids, glycosides, flavonoids and alkaloids. Total phenolic and total flavonoids of CA leaves were 5.50 ± 0.29 mg GAE /g and 23.00 ± 0.58 mg mg QE /g. Centella asiatica leaves is not hemotoxic in normal goat red blood cells. Free radical generation due to anaemia induced oxidative stress was restored with treatment with CA leaves in red blood cells of anaemic goats. Our data revealed that the extract exhibits an in-vitro protective effect on erythrocytes in anaemic goats.